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Search Results for " nk 1 "

Targets

53

Compounds

5

Natural Products

1761

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12233 NK-1 Antagonist 1 Rolapitant intermediate Others
NK-1 Antagonist 1 is a NK-1 receptor antagonist.
T8390 Cefazolin Others , Antibacterial , Antibiotic
Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.
T7396 Substance P(1-7) Substance P 1-7 Others , Neurokinin receptor
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects
T0953 Cefazolin sodium Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin Others , Antibacterial , Antibiotic
Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta...
T8235 L-732138 Neurokinin receptor
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
T9417L Gamma-preprotachykinin amide (72-92) acetate gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base) Others
gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate po...
T69140 Burapitant SSR 240600 Neurokinin receptor
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
T25615 Lanepitant LY303870,LY-303870,LY 303870 Others
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
T12000 MEN11467 Neurokinin receptor
MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.
TP1862L [Sar9] Substance P acetate(77128-75-7 free base) Neurokinin receptor
[Sar9]-Substance P acetate is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
T38144 Elinzanetant Neurokinin receptor
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.
T2539 Fingolimod hydrochloride Fingolimod (FTY720) HCl,FTY720 TRP/TRPV Channel , S1P Receptor , PAK , LPL Receptor
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
T28706 SCH 206272 SCH206272,SCH-206272
SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.
T70295 MDL-105212A HCl
MDL-105212A HCl is a nonpeptide NK-1 and NK-2 receptor antagonist.
T76405 [D-Trp2,7,9] Substance P
[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist that exhibits inhibitory affinities (K_i values) of 1 μM for NK-1, 1.3 μM for NK-2, and approximately 9 μM for NK-3 receptors [1].
T76431 GR 83074
GR 83074 is a potent and selective antagonist of the NK-2 (Neurokinin Receptor), demonstrating a selectivity factor of 340-fold over NK-1, with a pK B value of 8.23. It does not act as an antagonist for NK-3, affirming i...
T75880 GR 94800 TFA
GR 94800 TFA is a potent, selective antagonist of the NK 2 receptor peptide, demonstrating pK B values of 9.6 for NK 2, 6.4 for NK 1, and 6.0 for NK 3 receptors, respectively [1] [2].
T29186 YM49598 YM-49598,YM 49598
YM49598 is a tachykinin receptor antagonist. YM49598 exhibited high binding affinities at NK(1) (pK(i) = 9.09 +/- 0.02) and NK(2) (pK(i) = 9.94 +/- 0.03) receptors, respectively. YM49598 was almost inactive but produced ...
T4533 Serlopitant
Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.
T29185 YM44781 YM 44781,YM-44781
YM44781 is a non-peptide tachykinin receptor antagonist. YM44781 exhibits high binding affinities at NK(1) (pK(i) = 9.09 +/- 0.02) and NK(2) (pK(i) = 9.94 +/- 0.03) receptors, respectively.
TQ0087 NKP608 Neurokinin receptor
NKP608 is a selective and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50: 2.6 nM) and in vivo.
T75879 Men 10376 TFA
Men 10376 TFA is a selective antagonist of the tachykinin NK-2 receptor, displaying a K i value of 4.4 μM specifically for the NK-2 receptor in rat small intestine [1].
T76079 [Pro9]-Substance P
[Pro9]-Substance P is a highly effective, reversible, and selective agonist for NK-1 tachykinin receptors, demonstrating an EC50 value of 0.93 nM [1].
T69419 Vestipitant mesylate
Vestipitant mesylate is one of the most potent and selective NK(1) receptor antagonists ever discovered, showing appropriate pharmacokinetic properties and in vivo activity. Its actions support the utility of NK(1) recep...
T69420 Vestipitant
Vestipitant, also known as GW597599, is one of the most potent and selective NK(1) receptor antagonists ever discovered, showing appropriate pharmacokinetic properties and in vivo activity. Its actions support the utilit...
T76454 Substance P (5-11)
Substance P (5-11), the C-terminal heptapeptide derived from Substance P, functions as a neuropeptide. It specifically interacts with the NK-1 tachykinin receptor [1].
T75742 Neurokinin A(4-10) TFA
Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .
T76446 (D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P
(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P is a selective NK 1 receptor antagonist [1] .
T16406 Orvepitant maleate GW823296 maleate Neurokinin receptor
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chro...
T72820 (R)-Casopitant (R)-GW679769
(R)-Casopitant ((R)-GW679769), an isomer of Casopitant, functions as an NK(1)-receptor antagonist. It has applications in the study of chemotherapy-induced nausea and vomiting [1] [2].
T76428 (β-Ala8)-Neurokinin A (4-10)
(β-Ala8)-Neurokinin A (4-10), a neuropeptide, acts as a potent and selective agonist for the NK-2 tachykinin receptor [1].
T81077 Substance P(1-4)
Substance P(1-4) acts as a potent antagonist of neurokinin receptors (NK-R) and regulates normal hematopoiesis, additionally inhibiting the formation of endogenous erythroid colonies (EEC) [1].
T76453 Substance P (6-11)
Substance P (6-11), the C-terminal hexapeptideamide of Substance P, exhibits affinity for the NK-1 tachykinin receptor, leading to motoneuron depolarization and a hypotensive effect [1] [2].
T75769 [Sar9,Met(O2)11]-Substance P TFA
[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK 1 receptor selective agonist.
T36053 D-Lysine lactam
D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. 1.Kumar,...
T81513 Peptide A5K acetate
Peptide A5K acetate, an INF7-TAT derivative, facilitates CRISPR RNP delivery to T cells and effectively enhances Cas9 RNP transport to natural killer (NK) cells [1].
T76519 HCV Peptide (35-44)
HCV Peptide (35-44), a core protein of Hepatitis C Virus located at positions 35 to 44, functions as an HLA-A2-restricted CTL epitope and inhibits NK cell activity through two distinct mechanisms: directly through the KI...
T77034 Inbakicept N-803
Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). ...
TP1862 [Sar9] Substance P
[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
T80918 Tuparstobart Incagn-02385
Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic ...
T76897 Acasunlimab
Acasunlimab (GEN1046), a bispecific antibody (bsAb) designed to target PD-L1 and 4-1BB, functions by enhancing both T-cell and NK-cell response via conditional 4-1BB stimulation and continuously inhibiting the PD-1/PD-L1...
T75729 Neurokinin A TFA
Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter belonging to the tachykinin family, functions through the NK-2 receptor. It serves as a significant mediator in human airway and gastrointestinal tissues [1]...
T77096 Nemvaleukin alfa
Nemvaleukin alfa (ALKS 4230) is an IL-2 fusion protein that selectively targets intermediate-affinity IL-2R, serving as an activator of NK and effector T cells. This compound is utilized in cancer research [1] [2] [3].
T76436 [MePhe7]-Neurokinin B
[MePhe7]-Neurokinin B is a neurokinin NK-3 receptor (NK3R) agonist, exhibiting a potent agonistic activity with an IC50 value of 3 nM. It acts as a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) s...
T76435 Biotin-NeurokininA
Biotin-Neurokinin A, a biotinylated form of Neurokinin A (Substance K), functions as a peptide neurotransmitter within the tachykinin family, primarily engaging the NK-2 receptor. It serves as a significant mediator in t...
T82466 Englumafusp alfa RG6076,CD19-4-1BBL,RO7227166
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL, designed to induce CD19-specific 4-1BB cross-linking on the s...
TMIH-0236 Fingolimod-d4 HCl
Fingolimod-d4 HCl is a deuterated compound of Fingolimod HCl. Fingolimod HCl has a CAS number of 162359-56-0. Fingolimod, a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 an...
T76426 [Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), a Neurokinin A analogue, serves as a selective and potent agonist for the NK2 receptor (NK2R). This compound exhibits prokinetic activity, making it a valuable tool for re...
T37295 Ganglioside GM1 Asialo Mixture
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aer...
T74915 ODN D-SL03
ODN D-SL03, a class C CpG oligonucleotide, effectively stimulates peripheral blood mononuclear cells (PBMCs) to produce high levels of IFN-α. It activates human B cells, NK cells, and mononuclear cells, elevating the exp...

Compounds

NK-1 Antagonist 1
T12233
Synonym: Rolapitant intermediate
Target: Others
Cefazolin
T8390
Synonym:
Target: Others, Antibacterial, Antibiotic
Substance P(1-7)
T7396
Synonym: Substance P 1-7
Target: Others, Neurokinin receptor
Cefazolin sodium
T0953
Synonym: Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin
Target: Others, Antibacterial, Antibiotic
L-732138
T8235
Synonym:
Target: Neurokinin receptor
gamma-preprotachykinin amide (72-92) acetate
T9417L
Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)
Target: Others
Burapitant
T69140
Synonym: SSR 240600
Target: Neurokinin receptor
Lanepitant
T25615
Synonym: LY303870,LY-303870,LY 303870
Target: Others
MEN11467
T12000
Synonym:
Target: Neurokinin receptor
[Sar9] Substance P acetate(77128-75-7 free base)
TP1862L
Synonym:
Target: Neurokinin receptor
Elinzanetant
T38144
Synonym:
Target: Neurokinin receptor
Fingolimod hydrochloride
T2539
Synonym: Fingolimod (FTY720) HCl,FTY720
Target: TRP/TRPV Channel, S1P Receptor, PAK, LPL Receptor
SCH 206272
T28706
Synonym: SCH206272,SCH-206272
Target:
MDL-105212A HCl
T70295
Synonym:
Target:
[D-Trp2,7,9] Substance P
T76405
Synonym:
Target:
GR 83074
T76431
Synonym:
Target:
GR 94800 TFA
T75880
Synonym:
Target:
YM49598
T29186
Synonym: YM-49598,YM 49598
Target:
Serlopitant
T4533
Synonym:
Target:
YM44781
T29185
Synonym: YM 44781,YM-44781
Target:
NKP608
TQ0087
Synonym:
Target: Neurokinin receptor
Men 10376 TFA
T75879
Synonym:
Target:
[Pro9]-Substance P
T76079
Synonym:
Target:
Vestipitant mesylate
T69419
Synonym:
Target:
Vestipitant
T69420
Synonym:
Target:
Substance P (5-11)
T76454
Synonym:
Target:
Neurokinin A(4-10) TFA
T75742
Synonym:
Target:
(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P
T76446
Synonym:
Target:
Orvepitant maleate
T16406
Synonym: GW823296 maleate
Target: Neurokinin receptor
(R)-Casopitant
T72820
Synonym: (R)-GW679769
Target:
(β-Ala8)-Neurokinin A (4-10)
T76428
Synonym:
Target:
Substance P(1-4)
T81077
Synonym:
Target:
Substance P (6-11)
T76453
Synonym:
Target:
[Sar9,Met(O2)11]-Substance P TFA
T75769
Synonym:
Target:
D-Lysine lactam
T36053
Synonym:
Target:
Peptide A5K acetate
T81513
Synonym:
Target:
HCV Peptide (35-44)
T76519
Synonym:
Target:
Inbakicept
T77034
Synonym: N-803
Target:
[Sar9] Substance P
TP1862
Synonym:
Target:
Tuparstobart
T80918
Synonym: Incagn-02385
Target:
Acasunlimab
T76897
Synonym:
Target:
Neurokinin A TFA
T75729
Synonym:
Target:
Nemvaleukin alfa
T77096
Synonym:
Target:
[MePhe7]-Neurokinin B
T76436
Synonym:
Target:
Biotin-NeurokininA
T76435
Synonym:
Target:
Englumafusp alfa
T82466
Synonym: RG6076,CD19-4-1BBL,RO7227166
Target:
Fingolimod-d4 HCl
TMIH-0236
Synonym:
Target:
[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
T76426
Synonym:
Target:
Ganglioside GM1 Asialo Mixture
T37295
Synonym:
Target:
ODN D-SL03
T74915
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T7939 Fingolimod FTY-720A,FTY-720 S1P Receptor , PAK , LPL Receptor
Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
T3S1513 (20R)-Protopanaxadiol Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol Others , Antibacterial
1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...
T82429 Euphoheliosnoid A
Euphoheliosnoid A (Compound 24), a diterpenoid, significantly enhances natural killer (NK) cell-mediated cytotoxicity against H1299-luci cells and A549-luci cells at a concentration of 2.5 μM [1].
T82427 Euphoscopin C
Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1].
T35895 Ingenol 3,20-dibenzoate
Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the partic...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03290 HGF Protein, Mouse, Recombinant Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-01905 CD160 Protein, Human, Recombinant (His) Human HEK293 Cells
CD160 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is O95971-1.
TMPK-00062 CD160 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to...
TMPK-00058 CD94 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecul...
TMPY-05291 CD57/B3gat1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited down...
TMPJ-00220 B3GAT1 Protein, Human, Recombinant (His) Human HEK293 Cells
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lact...
TMPK-00059 CD94 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecul...
TMPJ-00567 NCR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPY-03237 HGF Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
HGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.8 kDa and the accession number is Q08048-1.
TMPJ-00097 NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252.
TMPK-01230 CLEC2D Protein, Human, Recombinant (hFc & Avi) Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclamps...
TMPJ-00425 NCR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Natural cytotoxicity triggering receptor 1(NKp46/NCR1) is a single-pass type I membrane protein. It consists of two extracellular Ig-like domains followed by a short stalk region, a transmembrane domain containing a posi...
TMPJ-00122 NKG2D/CD314 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709.
TMPK-00160 IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelia...
TMPK-00159 IL-15RA Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelia...
TMPK-00746 NKp46/NCR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00747 NKp46/NCR1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00955 CD161 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and de...
TMPK-00956 CD161 Protein, Human, Recombinant (His) Human HEK293 Cells
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in follow-up and de...
TMPK-00117 NKG2A/CD159a Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune c...
TMPK-00118 NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. NKG2A marks a unique immune effector subset preferentially co-expressing the tissue-resident CD103 molecule, but not immune c...
TMPK-00887 KIR3DL2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linke...
TMPK-00177 LAIR1 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that pla...
TMPK-00971 CRTAM Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPY-04040 CLEC2D Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were de...
TMPK-00134 ULBP-1 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00135 ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00721 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer...
TMPJ-00131 NKG2DL Protein, Human, Recombinant (hFc) Human HEK293 Cells
NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC ...
TMPJ-00187 CD300A Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD30...
TMPK-01165 MCEMP1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
A cecal ligation and puncture-induced sepsis mouse model was established to determine the expression of mast cell expression membrane protein 1 (MCEMP1). MCEMP1 in T lymphocytes isolated from sepsis mice were up- or down...
TMPJ-01432 CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated Human HEK293 Cells
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t...
TMPJ-00120 NKp80/KLRF1 Protein, Human, Recombinant (His) Human HEK293 Cells
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a ...
TMPJ-00281 CADM1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPJ-01337 IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Mouse HEK293 Cells
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f...
TMPJ-00898 CD72 Protein, Human, Recombinant (Trx & His) Human E. coli
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, mon...
TMPJ-00020 IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cel...
TMPK-01385 CRTAM Protein, Canine, Recombinant (His) Canine HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPJ-00363 IL-12RB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL1...
TMPJ-00070 IL-18 Protein, Human, Recombinant (His) Human HEK293 Cells
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPJ-00264 LAMP1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysoso...
TMPJ-00323 Nectin-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to me...
TMPY-02712 Serpin B3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was orig...
TMPJ-00831 CCL3 Protein, Mouse, Recombinant (His) Mouse E. coli
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His) Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPJ-01212 ULBP-1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
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HGF Protein, Mouse, Recombinant
TMPY-03290
Species: Mouse
Expression System: HEK293 Cells
CD160 Protein, Human, Recombinant (His)
TMPY-01905
Species: Human
Expression System: HEK293 Cells
CD160 Protein, Human, Recombinant (His & Avi)
TMPK-00062
Species: Human
Expression System: HEK293 Cells
CD94 Protein, Human, Recombinant (His & Avi)
TMPK-00058
Species: Human
Expression System: HEK293 Cells
CD57/B3gat1 Protein, Human, Recombinant (mFc)
TMPY-05291
Species: Human
Expression System: HEK293 Cells
B3GAT1 Protein, Human, Recombinant (His)
TMPJ-00220
Species: Human
Expression System: HEK293 Cells
CD94 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00059
Species: Human
Expression System: HEK293 Cells
NCR1 Protein, Human, Recombinant (hFc)
TMPJ-00567
Species: Human
Expression System: HEK293 Cells
HGF Protein, Mouse, Recombinant (His)
TMPY-03237
Species: Mouse
Expression System: HEK293 Cells
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00097
Species: Cynomolgus
Expression System: HEK293 Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi)
TMPK-01230
Species: Human
Expression System: HEK293 Cells
NCR1 Protein, Mouse, Recombinant (hFc)
TMPJ-00425
Species: Mouse
Expression System: HEK293 Cells
NKG2D/CD314 Protein, Mouse, Recombinant (His)
TMPJ-00122
Species: Mouse
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00160
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (His & Avi)
TMPK-00159
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (hFc)
TMPK-00746
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (mFc)
TMPK-00747
Species: Human
Expression System: HEK293 Cells
CD161 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00955
Species: Human
Expression System: HEK293 Cells
CD161 Protein, Human, Recombinant (His)
TMPK-00956
Species: Human
Expression System: HEK293 Cells
NKG2A/CD159a Protein, Human, Recombinant (His & Avi)
TMPK-00117
Species: Human
Expression System: HEK293 Cells
NKG2A/CD159a Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00118
Species: Human
Expression System: HEK293 Cells
KIR3DL2 Protein, Human, Recombinant (His & Avi)
TMPK-00887
Species: Human
Expression System: HEK293 Cells
LAIR1 Protein, Human, Recombinant (His & Avi)
TMPK-00177
Species: Human
Expression System: HEK293 Cells
CRTAM Protein, Mouse, Recombinant (His)
TMPK-00971
Species: Mouse
Expression System: HEK293 Cells
CLEC2D Protein, Rat, Recombinant (hFc)
TMPY-04040
Species: Rat
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi)
TMPK-00134
Species: Human
Expression System: HEK293 Cells
ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00135
Species: Human
Expression System: HEK293 Cells
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00721
Species: Mouse
Expression System: HEK293 Cells
NKG2DL Protein, Human, Recombinant (hFc)
TMPJ-00131
Species: Human
Expression System: HEK293 Cells
CD300A Protein, Human, Recombinant (hFc & His)
TMPJ-00187
Species: Human
Expression System: HEK293 Cells
MCEMP1 Protein, Mouse, Recombinant (hFc)
TMPK-01165
Species: Mouse
Expression System: HEK293 Cells
CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
TMPJ-01432
Species: Human
Expression System: HEK293 Cells
NKp80/KLRF1 Protein, Human, Recombinant (His)
TMPJ-00120
Species: Human
Expression System: HEK293 Cells
CADM1 Protein, Mouse, Recombinant (hFc)
TMPJ-00281
Species: Mouse
Expression System: HEK293 Cells
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
TMPJ-01337
Species: Mouse
Expression System: HEK293 Cells
CD72 Protein, Human, Recombinant (Trx & His)
TMPJ-00898
Species: Human
Expression System: E. coli
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00020
Species: Human
Expression System: HEK293 Cells
CRTAM Protein, Canine, Recombinant (His)
TMPK-01385
Species: Canine
Expression System: HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (hFc)
TMPJ-00363
Species: Human
Expression System: HEK293 Cells
IL-18 Protein, Human, Recombinant (His)
TMPJ-00070
Species: Human
Expression System: HEK293 Cells
LAMP1 Protein, Human, Recombinant (hFc)
TMPJ-00264
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Mouse, Recombinant (hFc)
TMPJ-00323
Species: Mouse
Expression System: HEK293 Cells
Serpin B3 Protein, Human, Recombinant (His)
TMPY-02712
Species: Human
Expression System: Baculovirus Insect Cells
CCL3 Protein, Mouse, Recombinant (His)
TMPJ-00831
Species: Mouse
Expression System: E. coli
IL-18 Protein, Mouse, Recombinant (His)
TMPJ-01056
Species: Mouse
Expression System: E. coli
ULBP-1 Protein, Mouse, Recombinant (His)
TMPJ-01212
Species: Mouse
Expression System: HEK293 Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293 Cells
TargetMol